Psoriasis clinical case: UVA 308 nm, calcipotriol, 8-week outcome — Z. Bahridinov, Radeski Skin Clinic Kokand.
Clinical Case: Comprehensive Psoriasis Treatment
Author: Z. Bahridinov · Clinic: Radeski Skin Clinic, Kokand
This article describes diagnosis, an individualized protocol, and 8-week outcomes in progressive plaque psoriasis.
Why the patient came
A 34-year-old man reported intensely itchy, red, scaling plaques on the scalp, elbows, and knees. Sleep and mood were affected.
Disease duration 3 years; sharp worsening over the last 2 months (season + work stress).
Prior treatments
Topical corticosteroids elsewhere and home remedies (herbal washes, tar soap).
Steroids gave short relief with rebound after stopping. Home remedies increased dryness and itch.
At presentation
- Phase: active, progressive
- Sites: scalp crown, both elbows and knees
- Psoriatic triad positive
- Diagnosis: vulgaris plaque psoriasis, progressive stage; moderate-to-severe PASI
Workup
Examination, scraping, punch biopsy, dermoscopy, CBC (ESR↑), liver/kidney labs, CRP, rheumatoid factor (negative).
Why this protocol?
Psoriasis is systemic autoimmune skin disease with 6–7× faster cell turnover. Topicals alone are not enough.
- Narrowband UVA 308 nm phototherapy
- Calcipotriol + zinc pyrithione (non-hormonal topicals)
- No systemic steroids — rebound risk to erythrodermic/pustular forms
Treatment course
Phototherapy 3×/week, 25 sessions; morning emollients and zinc cream; evening calcipotriol; medicated scalp care as prescribed; magnesium, B vitamins, hepatoprotectors; lifestyle advice for 8 weeks.
Outcome
Week 2 — itch resolved; week 4 — plaques flattened; week 8 — major clearance, ~95% PASI reduction, CRP normalized.
Physician comment
Long remission is achievable with the right combined therapy. UVA 308 nm + calcipotriol reduced steroid dependence. Erythrodermic psoriasis or psoriatic arthritis may require biologics or other systemic agents.
Related services: Phototherapy, Psoriasis school, Immunobiological therapy, Prices.
Can psoriasis be treated with cream only?
Sometimes in mild disease; moderate-to-severe progressive psoriasis usually needs phototherapy and a physician-led plan.
Why do steroid creams rebound?
Long-term use and abrupt withdrawal often trigger rebound flares — non-hormonal and device-based options matter.
How many UVA 308 nm sessions are needed?
Individual; in this case, three times weekly for 25 sessions total.